Study Goal:
To differentiate between the contributions of psychological stress and physical strain or exertion to preterm delivery and low birthweight. Both of these factors are associated with poor perinatal outcome. However, few studies focus on the separable and confounding effects of psychological stress and physical exertion or strain controlling for other determinants of birth outcomes such as medical complications, demographics and health behaviors.
Design:
A prospective and longitudinal study was conducted of over 400 women recruited from public, private and managed health care settings (HMOs). The sample was diverse in ethnicity, maternal risk conditions and parity. Women entered into the study before 20 weeks gestation and were studied at three times prenatally and once postpartum assessing perceived stress and physical strain through interview and biochemical samples (urinary catecholamine and plasma cortisol, CRH) as well as biophysical parameters (ultrasound at each visit). Health behaviors and social support were also assessed. Outcomes were obtained from medical charts.
Funded by NICHD “Stress Determinants of Low Birthweight and Preterm Birth”
PI: Calvin Hobel
CoPI: Chris Dunkel Schetter
CoInvestigators: Lony Castro, Larry Platt, Andrew Johnson, Linda Burnes-Bolton
Coding Manuals
Time 1 (09-13-1993): Questionnaire | Interview
Time 2 (07-25-1994): Questionnaire | Interview
Time 3 (07-25-1994): Questionnaire | Interview
Selected Publications
Hahn-Holbrook, J., Dunkel Schetter, C., Arora, C., & Hobel, C. J. (2013). Placental corticotropin-releasing hormone mediates the association between prenatal social support and postpartum depression. Clinical Psychological Science, 1(3), 253-265. https://doi.org/10.1177/2167702612470646 View file:
Gurung, R. A. R., Dunkel-Schetter, C., Collins, N., Rini, M., & Hobel, C. J. (2005). Psychosocial predictors of prenatal anxiety. Journal of Social and Clinical Psychology, 24(4), 497-519. https://doi.org/10.1521/jscp.2005.24.4.497 View file:
Parker-Dominguez, T., Dunkel-Schetter, C., Mancuso, R., Rini, C. M., & Hobel, C. J. (2005). Stress in African-American pregnancies: Testing the roles of various stress concepts in prediction of birth outcomes. Annals of Behavioral Medicine, 29(1), 12-21. https://doi.org/10.1207/s15324796abm2901_3 View file:
Mancuso, R. A., Dunkel-Schetter, C., Rini, C. M., Roesch, S.C., & Hobel, C. J. (2004). Maternal prenatal anxiety and corticotropin-releasing hormone associated with timing of delivery. Psychosomatic Medicine, 66, 762-769. https://doi.org/10.1097/01.psy.0000138284.70670.d5 View file:
Roesch, S. C., Dunkel-Schetter, C., Woo, G., & Hobel, C. J. (2004). Modeling the types and timing of stress in pregnancy. Anxiety, Stress, and Coping, 17(1), 87-102. https://doi.org/10.1080/1061580031000123667 View file:
Herrmann, T. S., Siega-Riz, A. M., Hobel, C. J., Aurora, C., & Dunkel-Schetter, C. (2001). Prolonged periods without food intake during pregnancy increases risk for elevated maternal corticotropin-releasing hormone concentrations. American Journal of Obstetrics and Gynecology, 185(2), 403-412. https://doi.org/10.1067/mob.2001.115863 View file:
Feldman,P. J., Dunkel-Schetter, C., Sandman, C. A., & Wadhwa, P. D. (2000). Maternal social support predicts birth weight and fetal growth in human pregnancy. Psychosomatic Medicine, 62(5), 715-725. https://doi.org/0033-3174/00/6205-0715
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Sagrestano, L. M., Feldman, P.,Killingsworth-Rini,C., Woo, G., & Dunkel-Schetter, C. (1999). Ethnicity and social support during pregnancy. American Journal of Community Psychology, 27(6), 873-902. https://doi.org/10.1023/A:1022266726892
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Hobel, C. J., Dunkel-Schetter, C., Roesch, S. C., Castro, L. C., & Arora, C. P. (1999). Maternal plasma corticotropin-releasing hormone associated with stress at 20 weeks’ gestation in pregnancies ending in preterm delivery. American Journal of Obstetrics and Gynecology, 180(1), S257-S263. https://doi.org/10.1016/S0002-9378(99)70712-X
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Hobel, C., Dunkel-Schetter, C., & Roesch, S. (1998). Maternal stress as a signal to the fetus. Prenatal and Neonatal Medicine, 3, 116-120. View file: Request from Authors
Dunkel-Schetter, C., Sagrestano, L., Feldman, P., & Killingsworth, C. (1996). Social support and pregnancy: A comprehensive review focusing on ethnicity and culture. In G. Pierce, B. Sarason, & I. Sarason (Eds.), Handbook of social support and the family (pp. 375-412). Plenum. View file: